Price range: $129.00 through $450.00
Pentosan polysulfate is a semi-synthetic polysulfated xylan used for the relief of Osteoarthritis. It can provide stimulation of cartilage matrix synthesis and prevention of cartilage breakdown. There are also systemic effects on blood lipid and fibrinolysis that may help clear the subchondral circulation.
Pentosan polysulfate is a semi-synthetic polysulfated xylan used for the relief of Osteoarthritis. The mechanism of PPS action in osteoarthritis is stimulation of cartilage matrix synthesis and prevention of cartilage breakdown. There are also systemic effects on blood lipid and fibrinolysis that may help clear the subchondral circulation. This is a subcutaneous injection self-administered twice a week for 6 weeks. Most patients have relief from symptoms within 1-2 weeks and may achieve full remission of symptoms in 2-6 months. The nasal spray is used once your symptoms have been in remission to prevent a relapse of inflammation and pain.
Formulation
<span style="font-weight: 400;">Pentosan Polysulfate (PPS) is an injectable therapy that can be used to help </span><b>reduce joint pain and inflammation</b><span style="font-weight: 400;"> in osteoarthritis.</span>
<span style="font-weight: 400;">It can aid in protecting cartilage, improving joint function, and decreasing pain by reducing inflammation and improving blood flow in affected joints.</span>
<span style="font-weight: 400;">Adults with osteoarthritis who want a non-opioid, non-steroidal option for managing joint pain.</span>
<span style="font-weight: 400;">Yes, as long as you’re not taking blood thinners or have contraindications determined by your provider.</span>
<span style="font-weight: 400;">Administered as a </span><b>subcutaneous injection</b><span style="font-weight: 400;">, typically 2 times weekly x 6 weeks, under the direction of a provider.</span>
<span style="font-weight: 400;">Follow your personalized schedule; typically, injections are spaced evenly through the week.</span>
<span style="font-weight: 400;">Doses are customized based on your weight and severity of osteoarthritis.</span>
<span style="font-weight: 400;">Some patients notice improvement within </span><b>4–6 weeks</b><span style="font-weight: 400;">, with continued progress over 8–12 weeks.</span>
<span style="font-weight: 400;">Pentosan polysulfate is prescribed as a 6 week course. Some patients notice full pain relief after 1 round. Other patients need 1-2 repeat rounds. It is often given as 3 courses per calendar year. </span>
<span style="font-weight: 400;">Yes, under medical supervision. It should </span><b>not</b><span style="font-weight: 400;"> be taken if you are using blood thinners due to increased bleeding risk.</span>
<span style="font-weight: 400;">Mild bruising at injection sites or temporary gastrointestinal discomfort are possible.</span>
<span style="font-weight: 400;">Yes. A prescription from a licensed provider is required.</span>
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<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Shipped securely to maintain sterility.</span></li>
<li><span style="font-weight: 400;">Store at room temperature, away from heat and light.</span><span style="font-weight: 400;">
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<span style="font-weight: 400;">Check Mobile Care Health’s website for </span><b>current pricing</b><span style="font-weight: 400;"> and </span><b><a href="https://mobilecarehealth.shop/product/mobile-care-rewards-membership/">Rewards Membership</a> discounts</b><span style="font-weight: 400;">.</span>
<span style="font-weight: 400;">PPS can help to reduce joint inflammation, protect cartilage, and improve blood flow to enhance joint repair and reduce pain.</span>
<span style="font-weight: 400;">Yes. Clinical studies show PPS can help improve pain and function in osteoarthritis patients.</span>
<span style="font-weight: 400;">Basic labs and a review of your medications are recommended to ensure safe use.</span>
<span style="font-weight: 400;">Yes. PPS can complement weight management, physical therapy, and anti-inflammatory diets.</span>
<span style="font-weight: 400;">Compounded medications are prepared by a state-licensed pharmacy for individual patients and have not been reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality. If FDA-approved medications in this class are available; your provider will discuss all options and determine what is appropriate for you. Individual results vary. All medication use requires medical supervision and ongoing lifestyle support.</span>
<b><a href="https://www.mobilecarehealth.com/book-now/">Book a consultation</a> with Mobile Care Health</b><span style="font-weight: 400;"> to see if PPS therapy is right for your joints.</span>
| Formulation | Nasal Spray, 5ml Vial for Injection, 2 – 5ml Vials for Injection, Capsules |
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